{"id":9011,"date":"2018-11-09T10:00:31","date_gmt":"2018-11-09T01:00:31","guid":{"rendered":"https:\/\/academist-cf.com\/journal\/?p=9011"},"modified":"2018-11-09T10:10:45","modified_gmt":"2018-11-09T01:10:45","slug":"%e7%a5%9e%e7%b5%8c%e5%b9%b9%e7%b4%b0%e8%83%9e%e3%81%ae%e9%81%8b%e5%91%bd%e3%82%92%e6%b1%ba%e5%ae%9a%e3%81%99%e3%82%8b%e3%80%8cmatrin-3%e3%80%8d%e3%82%92%e7%99%ba%e8%a6%8b%ef%bc%81-%e3%82%bf%e3%83%b3","status":"publish","type":"post","link":"https:\/\/academist-cf.com\/journal\/?p=9011","title":{"rendered":"\u795e\u7d4c\u5e79\u7d30\u80de\u306e\u904b\u547d\u3092\u6c7a\u5b9a\u3059\u308b\u300cMatrin-3\u300d\u3092\u767a\u898b\uff01 &#8211; 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id=\"attachment_9005\" aria-describedby=\"caption-attachment-9005\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-9005\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/001-1.jpg\" alt=\"\" width=\"600\" height=\"557\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/001-1.jpg 600w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/001-1-300x279.jpg 300w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/001-1-162x150.jpg 162w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9005\" class=\"wp-caption-text\">\u30de\u30a6\u30b9\u306e\u80ce\u4ed4\u8133\u304b\u3089\u5206\u53d6\u30fb\u57f9\u990a\u3057\u305f\u795e\u7d4c\u7d30\u80de\u306bFGF\u523a\u6fc0\u3092\u884c\u3044\u3001\u6838\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u62bd\u51fa\u3057\u305f\u5f8c\u3001\u4e8c\u6b21\u5143\u96fb\u6c17\u6cf3\u52d5\u3067\u5206\u96e2\u3057\u305f\u7d50\u679c\u3001Matrin-3\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u767a\u898b\u3057\u305f<\/figcaption><\/figure>\n<h3>Matrin-3\u306e\u767a\u73fe\u3068\u30ea\u30f3\u9178\u5316\u306f\u795e\u7d4c\u5e79\u7d30\u80de\u306e\u672a\u5206\u5316\u6027\u3092\u7dad\u6301\u3059\u308b<\/h3>\n<p>\u30de\u30a6\u30b9\u306e\u80ce\u4ed4\u8133\u304b\u3089\u63a1\u53d6\u30fb\u57f9\u990a\u3057\u305f\u795e\u7d4c\u5e79\u7d30\u80de\u306b\u3001\u5897\u6b96\u56e0\u5b50\uff08FGF2\uff09\u3092\u7528\u3044\u3066\u672a\u5206\u5316\u523a\u6fc0\u3092\u4e0e\u3048\u305f\u3068\u3053\u308d\u3001Matrin-3\u304c\u9ad8\u767a\u73fe\u3057\u30ea\u30f3\u9178\u5316\u304c\u9032\u3093\u3067\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u80ce\u751f\u671f\u306e\u8133\u306b\u304a\u3051\u308bMatrin-3\u306e\u767a\u73fe\u3092\u8abf\u3079\u305f\u3068\u3053\u308d\u3001Matrin-3\u306f\u795e\u7d4c\u5e79\u7d30\u80de\u304c\u8c4a\u5bcc\u306b\u5b58\u5728\u3059\u308b\u300c\u8133\u5ba4\u5e2f\u300d\u300c\u8133\u5ba4\u4e0b\u5e2f\u300d\u300c\u6d77\u99ac\u6b6f\u72b6\u56de\u300d\u3068\u547c\u3070\u308c\u308b\u9818\u57df\u306b\u591a\u304f\u767a\u73fe\u3057\u3001\u3055\u3089\u306b\u305d\u308c\u3089\u306e\u9818\u57df\u306b\u304a\u3044\u3066Matrin-3\u306f\u30ea\u30f3\u9178\u5316\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<figure id=\"attachment_9007\" aria-describedby=\"caption-attachment-9007\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-9007\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/003.jpg\" alt=\"\" width=\"600\" height=\"392\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/003.jpg 600w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/003-300x196.jpg 300w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/003-230x150.jpg 230w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9007\" class=\"wp-caption-text\">E14.5\u30de\u30a6\u30b9cortex\u306b\u304a\u3051\u308b\u30ea\u30f3\u9178\u5316Matrin-3\uff08P-Matrin-3\uff09<br 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id=\"attachment_9006\" aria-describedby=\"caption-attachment-9006\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-9006\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/002-1.jpg\" alt=\"\" width=\"600\" height=\"316\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/002-1.jpg 600w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/002-1-300x158.jpg 300w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/002-1-280x147.jpg 280w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9006\" class=\"wp-caption-text\">\u795e\u7d4c\u5e79\u7d30\u80de\uff08\u5de6\u56f3\uff09\u306bMatrin-3-siRNA\u3092\u5c0e\u5165\u3057Matrin-3\u3092\u6b20\u640d\u3055\u305b\u308b\u3068\u3001\u7a81\u8d77\u4f38\u9577\u304c\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\uff08\u53f3\u56f3\uff09<\/figcaption><\/figure>\n<figure id=\"attachment_9008\" aria-describedby=\"caption-attachment-9008\" style=\"width: 504px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-9008\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/004.jpg\" alt=\"\" width=\"504\" height=\"552\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/004.jpg 504w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/004-274x300.jpg 274w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/004-137x150.jpg 137w\" sizes=\"auto, (max-width: 504px) 100vw, 504px\" \/><figcaption id=\"caption-attachment-9008\" class=\"wp-caption-text\">Matrin-3\u306ein utero 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id=\"attachment_9009\" aria-describedby=\"caption-attachment-9009\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-9009\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/005.jpg\" alt=\"\" width=\"600\" height=\"384\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/005.jpg 600w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/005-300x192.jpg 300w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2018\/11\/005-234x150.jpg 234w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9009\" class=\"wp-caption-text\">\u795e\u7d4c\u5e79\u7d30\u80de\u306b\u304a\u3051\u308bMatrin-3\u306e\u9ad8\u3044\u767a\u73fe\u3068\u30ea\u30f3\u9178\u5316\u306e\u4ea2\u9032\u306f\u3001\u795e\u7d4c\u5e79\u7d30\u80de\u306e\u672a\u719f\u6027\u3092\u7dad\u6301\u3059\u308b<\/figcaption><\/figure>\n<h3>Matrin-3\u3068\u5bb6\u65cf\u6027ALS &#8211; \u8fd1\u5e74\u306e\u5831\u544a\u3088\u308a<\/h3>\n<p>\u8fd1\u5e74\u306e\u7814\u7a76\u5831\u544a\u304b\u3089\u3001Matrin-3\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u5bb6\u65cf\u6027\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\uff08\u5bb6\u65cf\u6027ALS\uff09\u3092\u5f15\u304d\u8d77\u3053\u3059\u8cac\u4efb\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u307e\u3057\u305f\u3002 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\/>\nKanako Niimori-Kita et al., Matrin-3 is essential for fibroblast growth factor 2-dependent maintenance of neural stem cells, Scientific Reports, 8, 13412 (2018) doi:10.1038\/s41598-018-31597-x<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u795e\u7d4c\u5e79\u7d30\u80de\u306e\u904b\u547d\u3092\u6c7a\u5b9a\u3059\u308b\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u306f\uff1f \u795e\u7d4c\u5e79\u7d30\u80de\u306f\u3055\u307e\u3056\u307e\u306a\u795e\u7d4c\u7d30\u80de\u306b\u5206\u5316\u3059\u308b\u591a\u5206\u5316\u80fd\u3068\u3001\u672a\u5206\u5316\u306e\u307e\u307e\u81ea\u5df1\u8907\u88fd\u3059\u308b\u80fd\u529b\u3068\u3092\u3042\u308f\u305b\u6301\u3063\u305f\u7d30\u80de\u3067\u3059\u3002\u54fa\u4e73\u985e\u306e\u80ce\u751f\u671f\u306b\u304a\u3044\u3066\u306f\u3001\u8133\u3092\u69cb\u6210\u3059\u308b\u4e3b\u8981\u306a\u7d30 [&hellip;]<\/p>\n","protected":false},"author":349,"featured_media":9007,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[3],"tags":[55,82,15,40],"class_list":["post-9011","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-outcome","tag-55","tag-82","tag-biology","tag-40","has_thumb"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/9011","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/users\/349"}],"replies":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9011"}],"version-history":[{"count":18,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/9011\/revisions"}],"predecessor-version":[{"id":9112,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/9011\/revisions\/9112"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/media\/9007"}],"wp:attachment":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9011"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9011"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}