{"id":6352,"date":"2017-11-08T10:00:02","date_gmt":"2017-11-08T01:00:02","guid":{"rendered":"https:\/\/dev.academist-cf.com\/journal\/?p=6352"},"modified":"2019-04-04T17:37:55","modified_gmt":"2019-04-04T08:37:55","slug":"%e9%87%8d%e5%ba%a6%e3%81%ae%e3%82%b9%e3%83%88%e3%83%ac%e3%82%b9%e3%81%a7%e8%90%8e%e7%b8%ae%e3%81%99%e3%82%8b%e3%81%ae%e3%81%af%e6%84%9f%e8%a6%9a%e7%b3%bb%e3%81%ae%e8%84%b3%e9%83%a8%e4%bd%8d%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/academist-cf.com\/journal\/?p=6352","title":{"rendered":"\u91cd\u5ea6\u306e\u30b9\u30c8\u30ec\u30b9\u3067\u840e\u7e2e\u3059\u308b\u306e\u306f\u611f\u899a\u7cfb\u306e\u8133\u90e8\u4f4d\uff1f\uff01"},"content":{"rendered":"

\u30b9\u30c8\u30ec\u30b9\u3068\u7cbe\u795e\u75be\u60a3\u306e\u6df1\u304f\u3066\u5fae\u5999\u306a\u95a2\u4fc2<\/h3>\n

\u8aad\u8005\u306e\u7686\u3055\u3093\u306e\u306a\u304b\u306b\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u3067\u7cbe\u795e\u7684\u306b\u8f9b\u3044\u601d\u3044\u3092\u3057\u305f\u3068\u3044\u3046\u65b9\u306f\u305f\u304f\u3055\u3093\u3044\u3089\u3063\u3057\u3083\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u3000\u30b9\u30c8\u30ec\u30b9\u3092\u53d7\u3051\u3066\u5fc3\u306e\u75c5\u306b\u304b\u304b\u308b\u3068\u3044\u3046\u6587\u8108\u306f\u591a\u304f\u306e\u65b9\u306b\u7406\u89e3\u3057\u3084\u3059\u304f\u3001\u3053\u308c\u3092\u304d\u3063\u304b\u3051\u3068\u3057\u3066\u7cbe\u795e\u79d1\u3092\u53d7\u8a3a\u3059\u308b\u3068\u3044\u3046\u65b9\u3082\u305f\u304f\u3055\u3093\u3044\u307e\u3059\u3002<\/p>\n

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\n\n<\/div>\n

\u52d5\u7269\u30e2\u30c7\u30eb\u3067\u306e\u5b9f\u9a13<\/h3>\n

\u3053\u308c\u307e\u3067\u306ePTSD\u306e\u81e8\u5e8a\u753b\u50cf\u7814\u7a76\u306b\u304a\u3044\u3066\u306f\u3001\u524d\u90e8\u5e2f\u72b6\u56de\u30fb\u6d77\u99ac\u30fb\u6241\u6843\u4f53\u306a\u3069\u306e\u8133\u840e\u7e2e\u304c\u5831\u544a\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u6a2a\u65ad\u7684\u306a\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u7814\u7a76\u3082\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e0a\u8a18\u306b\u8ff0\u3079\u305f\u30b9\u30c8\u30ec\u30b9\u3068\u306e\u56e0\u679c\u95a2\u4fc2\u3092\u660e\u78ba\u306b\u3059\u308b\u3053\u3068\u306f\u3084\u306f\u308a\u96e3\u3057\u3044\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n

\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u6050\u6016\u5b66\u7fd2\u95a2\u9023\u306e\u5b9f\u9a13\u304c\u3053\u308c\u307e\u3067\u6570\u591a\u304f\u3055\u308c\u3066\u304a\u308a\u3001PTSD\u306e\u75c7\u72b6\u3068\u305d\u306e\u7d50\u679c\u306f\u304b\u306a\u308a\u985e\u4f3c\u3057\u3066\u3044\u307e\u3059\u3002PTSD\u306e\u30e2\u30c7\u30eb\u30b9\u30c8\u30ec\u30b9\u306b\u3064\u3044\u3066\u3082\u3044\u304f\u3064\u304b\u63d0\u5531\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001Single\u3000prolonged stress\uff08\u4ee5\u4e0bSPS\uff09\u3068\u3044\u3046\u30e2\u30c7\u30eb\u3092\u4eca\u56de\u306f\u91cd\u5ea6\u306e\u30b9\u30c8\u30ec\u30b9\u3068\u3057\u3066\u63a1\u7528\u3057\u3066\u3044\u307e\u3059\u3002PTSD\u60a3\u8005\u306b\u304a\u3044\u3066\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u306e\u5206\u6ccc\u304c\u6291\u5236\u3055\u308c\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u3001\u4eca\u56de\u306f\u884c\u52d5\u9762\u306e\u5831\u544a\u3068\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u52d5\u614b\u306e\u53cc\u65b9\u304c\u985e\u4f3c\u3057\u3066\u3044\u308b\u70b9\u304c\u3053\u306e\u30e2\u30c7\u30eb\u306e\u5f37\u307f\u3067\u3059\u3002<\/p>\n

\u79c1\u305f\u3061\u306f\u3053\u306e\u52d5\u7269\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3001\u4eba\u9593\u306e\u81e8\u5e8a\u7814\u7a76\u3068\u540c\u3058\u65b9\u6cd5\uff08\u3059\u306a\u308f\u3061\u8133MRI\u64ae\u5f71\uff09\u3067\u89e3\u6790\u3059\u308b\u3068\u3044\u3046\u7814\u7a76\u3092\u4f01\u753b\u3057\u307e\u3057\u305f\u3002\u52d5\u7269\u3067\u5f97\u3089\u308c\u305f\u7d50\u679c\u3092\u4eba\u306e\u7814\u7a76\u306b\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u3057\u3084\u3059\u3044\u3068\u8003\u3048\u305f\u304b\u3089\u3067\u3059\u3002\u307e\u305f\u3001\u30b9\u30c8\u30ec\u30b9\u3092\u8ca0\u8377\u3059\u308b\u3068\u3044\u3046\u64cd\u4f5c\u306b\u3088\u3063\u3066\u5f97\u3089\u308c\u308b\u76f4\u63a5\u306e\u7d50\u679c\u3067\u3042\u308b\u3053\u3068\u3092\u4eca\u56de\u306f\u91cd\u8996\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u52d5\u7269\u5b9f\u9a13\u3067\u3042\u308c\u3070\u751f\u6d3b\u74b0\u5883\u30fb\u907a\u4f1d\u7684\u7d20\u56e0\u306a\u3069\u3092\u63c3\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u306e\u3067\u3001\u305d\u308c\u304c\u53ef\u80fd\u3060\u3068\u8003\u3048\u305f\u306e\u3082\u7406\u7531\u3067\u3059\u3002<\/p>\n

\u89e3\u6790\u306e\u624b\u6cd5\u306f\u3001\u300cvoxel based morphometry\u300d\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u3002\u3053\u308c\u306fMRI\u753b\u50cf\u306b\u304a\u3051\u308b\u8133\u5168\u4f53\u3092\u7d30\u304b\u306a\u30dc\u30af\u30bb\u30eb\uff082\u6b21\u5143\u753b\u50cf\u306b\u304a\u3051\u308b\u30d4\u30af\u30bb\u30eb\u3042\u308b\u3044\u306f\u30c9\u30c3\u30c8\uff09\u5358\u4f4d\uff08\u672c\u7814\u7a76\u3067\u306f0.137 \u00d7 0.137 \u00d7 0.137mm3<\/sup>\uff09\u3054\u3068\u306b\u7d71\u8a08\u89e3\u6790\u3057\u3001\u8133\u4f53\u7a4d\u306e\u6e1b\u5c11\u3084\u5897\u52a0\u3092\u89e3\u6790\u3059\u308b\u691c\u5b9a\u624b\u6cd5\u3067\u3059\u3002\u753b\u50cf\u89e3\u50cf\u5ea6\u304b\u3089\u306f100\u4e07\u56de\u4ee5\u4e0a\u306e\u691c\u5b9a\u56de\u6570\u3068\u306a\u308a\u307e\u3059\u306e\u3067\u691c\u51fa\u529b\u306f\u6c7a\u3057\u3066\u9ad8\u3044\u3068\u306f\u3044\u3048\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u5168\u8133\u3092\u7db2\u7f85\u7684\u306b\u7d71\u8a08\u51e6\u7406\u3067\u304d\u308b\u306e\u3067\u7814\u7a76\u30d0\u30a4\u30a2\u30b9\u304c\u5165\u308b\u4f59\u5730\u304c\u5c11\u306a\u3044\u624b\u6cd5\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n

\u305f\u3060\u3057\u3001\u975e\u5e38\u306b\u7cbe\u7d30\u306a\u753b\u50cf\u304c\u8981\u6c42\u3055\u308c\u308b\u305f\u3081\u3001\u52d5\u7269\u306e\u64ae\u5f71\u3067\u306f\u4f53\u52d5\u306b\u3088\u308b\u30ce\u30a4\u30ba\u306a\u3069\u306e\u305f\u3081\u64ae\u50cf\u30af\u30aa\u30ea\u30c6\u30a3\u306e\u9762\u3067\u89e3\u6790\u56f0\u96e3\u306a\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4eca\u56de\u306f\u704c\u6d41\u56fa\u5b9a\u3057\u3066\u982d\u84cb\u9aa8\u3054\u3068\u8133\u3092\u6458\u51fa\u3057\u3066\u64ae\u5f71\u3059\u308b\u3068\u3044\u3046\u30d7\u30ed\u30c8\u30b3\u30fc\u30eb\u3092\u7528\u3044\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u691c\u51fa\u3055\u308c\u305f\u90e8\u4f4d\u306b\u5bfe\u3057\u3066\u9855\u5fae\u93e1\u89e3\u6790\u3067\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u78ba\u8a8d\u3059\u308b\u3088\u3046\u306a\u5b9f\u9a13\u3092\u4f01\u753b\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u5b9f\u9a13\u306e\u7d50\u679c<\/h3>\n

50\u65e5\u9f62\u30fb\u96c4\u6027\u306eSprague Dawley\u30e9\u30c3\u30c8\u306bSPS\u3092\u8ca0\u8377\u3057\u3001\u8ca0\u8377\u5f8c7\u65e5\u5f8c\u306b\u704c\u6d41\u56fa\u5b9a\u3057\u8133\u3092\u982d\u84cb\u9aa8\u3054\u3068\u6458\u51fa\u3057\u307e\u3057\u305f\u3002\u5bfe\u7167\uff08Sham\uff09\u306f\u8efd\u5fae\u306a\u30b9\u30c8\u30ec\u30b9\u3068\u3057\u3066\u30a8\u30fc\u30c6\u30eb\u9ebb\u9154\u306e\u307f\u8ca0\u8377\u3057\u3001\u540c\u69d8\u306e\u51e6\u7f6e\u3092\u884c\u3044\u307e\u3059\u3002\u6a2a\u7f6e\u304d\u578bMRI\uff08Agilent\u793e\u88fd\u3001\u6a2a\u7f6e\u304d\u578b\u30de\u30b0\u30cd\u30c3\u30c8\u30017.04T\u3001\u30dc\u30a2\u5f84310mm\uff09\u3092\u7528\u3044\u3066\u3001SPS\u7fa4\uff08n=18\uff09Sham\u7fa4(n=17)\u306b\u3064\u3044\u3066\u982d\u90e8MRI\u64ae\u5f71\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n

Voxel based morphometry\u3092\u7528\u3044\u305f\u753b\u50cf\u89e3\u6790\u306e\u7d50\u679c\u3068\u3057\u3066\u3001\u53f3\u8996\u899a\u91ce\u304a\u3088\u3073\u4e21\u5074\u8996\u5e8a\u306b\u304a\u3051\u308b\u8133\u840e\u7e2e\u304c\u5224\u660e\u3057\u307e\u3057\u305f\u3002<\/p>\n

\"\"
Voxel based morphometry\u3092\u7528\u3044\u305f\u753b\u50cf\u89e3\u6790\u306e\u7d50\u679c\uff08height threshold p<0.001, cluster-FWE corrected P<0.05\uff09<\/figcaption><\/figure>\n

\u79c1\u305f\u3061\u306f\u30b9\u30c8\u30ec\u30b9\u3068\u306e\u56e0\u679c\u95a2\u4fc2\u306b\u3088\u3063\u3066\u3082\u305f\u3089\u3055\u308c\u305f\u7d50\u679c\u3067\u3042\u308b\u3053\u3068\u3092\u91cd\u8996\u3057\u3066\u3044\u307e\u3059\u3002\u8ffd\u52a0\u5b9f\u9a13\u3068\u3057\u3066\u5b9f\u9a13\u3067\u5224\u660e\u3057\u305f\u840e\u7e2e\u90e8\u4f4d\u306b\u304a\u3044\u3066\u3001\u5f97\u3089\u308c\u305f\u7d50\u679c\u304c\u30b9\u30c8\u30ec\u30b9\u4ee5\u5916\u306e\u5b9f\u9a13\u5185\u64cd\u4f5c\u306b\u3088\u3063\u3066\u5f97\u3089\u308c\u305f\u3082\u306e\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u691c\u8a3c\u3057\u305f\u3044\u3068\u8003\u3048\u3001\u30b9\u30c8\u30ec\u30b9\u5f8c\u306b\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u306b\u3064\u3044\u3066\u89e3\u6790\u3057\u307e\u3057\u305f\u3002\u624b\u6cd5\u3068\u3057\u3066\u306f\u6d3b\u6027\u5316\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u306e\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308bIba-1\u306b\u5bfe\u3059\u308b\u6297\u4f53\u3092\u7528\u3044\u3066\u86cd\u5149\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u3092\u884c\u3063\u3066\u3044\u307e\u3059\uff08SPS\uff1an=5, Sham: n=6\uff09\u3002<\/p>\n

\u67d3\u8272\u3055\u308c\u305fIba-1\u967d\u6027\u7d30\u80de\u306e\u6570\u30fb\u7d30\u80de\u306e\u5927\u304d\u3055\u306e\u5e73\u5747\u5024\u3092\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u8996\u899a\u91ce\u3067\u306f\u53cc\u65b9\u3068\u3082\u6709\u610f\u306b\u5897\u5927\u3057\u3001\u8996\u5e8a\u3067\u306f\u7d30\u80de\u306e\u5927\u304d\u3055\u306e\u307f\u3067\u3059\u304c\u6709\u610f\u306b\u5897\u5927\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u7d50\u8ad6\u3068\u3057\u3066\u3053\u308c\u3089\u306e\u9818\u57df\u30ec\u30d9\u30eb\u3067\u3001\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u304c\u6d3b\u6027\u5316\u3057\u3066\u304a\u308a\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u304c\u3042\u3063\u305f\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n

\"\"
\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u6d3b\u6027\u5316\u89e3\u6790\u306e\u7d50\u679c\uff08Iba-1: <\/span>\u6d3b\u6027\u5316\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u306e\u30de\u30fc\u30ab\u30fc
Neurotrace : \u795e\u7d4c\u7d30\u80de\u306e\u30de\u30fc\u30ab\u30fc\uff09<\/span><\/figcaption><\/figure>\n

\u7d50\u679c\u306f\u30b9\u30c8\u30ec\u30b9\u3088\u308a\u75db\u307f\u306b\u4f3c\u3066\u3044\u308b<\/h3>\n

\u3053\u308c\u307e\u3067\u306e\u52d5\u7269\u5b9f\u9a13\u306e\u7814\u7a76\u304b\u3089\u306f\u3001\u6050\u6016\u5b66\u7fd2\u306b\u3088\u308b\u884c\u52d5\u5909\u5316\u3068PTSD\u306e\u75c7\u72b6\u306f\u985e\u4f3c\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u81e8\u5e8a\u7814\u7a76\u3067\u3082\u6d77\u99ac\u30fb\u6241\u6843\u4f53\u30fb\u524d\u90e8\u5e2f\u72b6\u56de\u306a\u3069\u6050\u6016\u5b66\u7fd2\u3068\u95a2\u9023\u3057\u305f\u8133\u840e\u7e2e\u306e\u5831\u544a\u304c\u3042\u308a\u3001\u5b9f\u306e\u3068\u3053\u308d\u4eca\u56de\u306e\u7814\u7a76\u3067\u3082\u3001\u3053\u308c\u3089\u306b\u76f8\u5f53\u3059\u308b\u90e8\u4f4d\u3067\u306e\u8133\u840e\u7e2e\u304c\u91cd\u5ea6\u306e\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u3063\u3066\u751f\u3058\u308b\u3068\u79c1\u305f\u3061\u306f\u4e88\u60f3\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u7d50\u679c\u304b\u3089\u306f\u3001\u3053\u308c\u3089\u306e\u90e8\u4f4d\u3067\u306f\u6709\u610f\u306a\u8133\u840e\u7e2e\u3092\u691c\u51fa\u3067\u304d\u305a\u3001\u8996\u899a\u91ce\u30fb\u8996\u5e8a\u306a\u3069\u611f\u899a\u7cfb\u306e\u8133\u90e8\u4f4d\u3067\u840e\u7e2e\u3092\u691c\u51fa\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u4e88\u60f3\u5916\u306e\u7d50\u679c\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u65b0\u767a\u898b\u3067\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u679c\u305f\u3057\u3066\u3053\u306e\u767a\u898b\u304c\u59a5\u5f53\u306a\u306e\u304b\u3069\u3046\u304b\u306f\u4eca\u5f8c\u306e\u7814\u7a76\u3092\u542b\u3081\u3066\u8b70\u8ad6\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u79c1\u305f\u3061\u306e\u7814\u7a76\u306f\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u3042\u308a\u307e\u3059\u304c\u3001PTSD\u3088\u308a\u3082\u3080\u3057\u308d\u75bc\u75db\u306b\u985e\u4f3c\u3057\u305f\u7d50\u679c\u306b\u306a\u3063\u3066\u3057\u307e\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u30b9\u30c8\u30ec\u30b9\u6027\u7cbe\u795e\u75be\u60a3\u3067\u306e\u60a3\u8005\u306e\u8996\u899a\u91ce\u306e\u8133\u840e\u7e2e\u306e\u5831\u544a\u306f\u5c11\u306a\u3044\u3067\u3059\u304c\u30bc\u30ed\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4e00\u65b9\u3067\u8996\u5e8a\u306b\u3064\u3044\u3066\u306f\u30b9\u30c8\u30ec\u30b9\u6027\u7cbe\u795e\u75be\u60a3\u3067\u306e\u840e\u7e2e\u306e\u5831\u544a\u306f\u307b\u307c\u3042\u308a\u307e\u305b\u3093\u3002\u9006\u306b\u3001\u8996\u5e8a\u306e\u840e\u7e2e\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u7814\u7a76\u306f\u4f55\u304b\uff1f \u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308b\u3068\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u8fd1\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u5206\u91ce\u306e\u3082\u306e\u3067\u306f\u75bc\u75db\u95a2\u9023\u306e\u7814\u7a76\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u91cd\u5ea6\u306e\u75bc\u75db\u3092\u4f34\u3046\u810a\u9ac4\u640d\u50b7\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u3001\u8996\u899a\u91ce\u306e\u840e\u7e2e\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u810a\u9ac4\u640d\u50b7\u306e\u60a3\u8005\u3055\u3093\u3092\u60f3\u5b9a\u3059\u308c\u3070\u3001\u539f\u56e0\u3068\u306a\u3063\u305f\u4e8b\u6545\u306a\u3069\u306fPTSD\u306b\u306a\u3063\u3066\u3082\u304a\u304b\u3057\u304f\u306a\u3044\u30b9\u30c8\u30ec\u30b9\u4f53\u9a13\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3057\u3001\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u3068\u75db\u307f\u306f\u8133\u304b\u3089\u3059\u308c\u3070\u985e\u4f3c\u3057\u305f\u523a\u6fc0\u3067\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u3042\u308a\u5f97\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u307e\u305f\u3001\u300c\u5fc3\u306e\u75db\u307f\u300d\u3068\u3044\u3046\u8a00\u8449\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u307e\u3055\u306b\u305d\u306e\u3068\u304a\u308a\u306e\u7d50\u679c\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u8996\u899a\u51e6\u7406\u306f\u30b9\u30c8\u30ec\u30b9\u7814\u7a76\u306e\u30d5\u30ed\u30f3\u30c6\u30a3\u30a2<\/h3>\n

\u79c1\u305f\u3061\u306e\u7814\u7a76\u3067\u5f97\u3089\u308c\u305f\u8996\u899a\u91ce\u3084\u8996\u5e8a\u3068\u3044\u3046\u90e8\u4f4d\u306fPTSD\u306e\u7814\u7a76\u3068\u3057\u3066\u306f\u4e88\u60f3\u5916\u306e\u7d50\u679c\u3067\u3042\u3063\u305f\u3053\u3068\u306f\u524d\u8ff0\u3057\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u8996\u70b9\u3092\u5909\u3048\u308b\u3068PTSD\u306b\u306f\u518d\u4f53\u9a13\u3068\u3044\u3046\u75c7\u72b6\u304c\u3042\u308a\u3001\u3057\u3070\u3057\u3070\u300c\u30b9\u30c8\u30ec\u30b9\u306e\u5834\u9762\u304c\u898b\u3048\u308b\u300d\u3068\u3044\u3046\u60a3\u8005\u3055\u3093\u306e\u8a34\u3048\u304c\u3042\u308a\u307e\u3059\u3002\u79c1\u305f\u3061\u306f\u3053\u308c\u307e\u3067\u306e\u6050\u6016\u5b66\u7fd2\u7406\u8ad6\u3067\u306f\u3053\u306e\u898b\u3048\u308b\u3068\u3044\u3046\u73fe\u8c61\u306e\u8aac\u660e\u304c\u6975\u3081\u3066\u96e3\u3057\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u7cbe\u795e\u79d1\u533b\u306a\u3089\u8ab0\u3082\u304c\u3053\u306e\u73fe\u8c61\u3092\u77e5\u3063\u3066\u3044\u306a\u304c\u3089\u3001\u898b\u3048\u308b\u3068\u3044\u3046\u3053\u3068\u306b\u95a2\u9023\u3057\u305d\u3046\u306a\u8996\u899a\u91ce\u306b\u3064\u3044\u3066\u306fPTSD\u306e\u7814\u7a76\u3068\u3057\u3066\u306f\u75c5\u56e0\u8ad6\u7684\u306b\u8b70\u8ad6\u3055\u308c\u3066\u3053\u306a\u304b\u3063\u305f\u9818\u57df\u306a\u306e\u3067\u3059\u3002<\/p>\n

\u4e00\u65b9\u3067\u306f\u3001\u8996\u899a\u91ce\u3092\u4ecb\u3055\u306a\u3044\u8996\u899a\u51e6\u7406\u7d4c\u8def\uff08\u7db2\u819c\u301c\u4e2d\u8133\u4e0a\u4e18\u301c\u6241\u6843\u4f53\u3078\u306e\u7d4c\u8def\uff09\u304c\u6050\u6016\u53cd\u5fdc\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u3001\u8996\u899a\u91ce\u304c\u840e\u7e2e\u3057\u305f\u79c1\u305f\u3061\u306e\u5831\u544a\u3068\u306e\u95a2\u9023\u3092\u691c\u8a3c\u3059\u308b\u3053\u3068\u306f\u4eca\u5f8c\u306e\u9b45\u529b\u7684\u306a\u7814\u7a76\u8ab2\u984c\u3067\u3059\u3002\u307e\u305f\u3001\u4eba\u9593\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u306f\u8996\u899a\u30bf\u30b9\u30af\u30b2\u30fc\u30e0\uff08\u30c6\u30c8\u30ea\u30b9\uff09\u3067PTSD\u3092\u4e88\u9632\u3067\u304d\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u4eca\u56de\u5831\u544a\u3055\u308c\u305f\u90e8\u4f4d\u306b\u3064\u3044\u3066\u5b9f\u969b\u306e\u81e8\u5e8a\u7814\u7a76\u3067\u691c\u8a3c\u3055\u308c\u3001\u8a3a\u65ad\u30fb\u6cbb\u7642\u304c\u5909\u5316\u3059\u308b\u53ef\u80fd\u6027\u306f\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u53c2\u8003\u6587\u732e<\/strong>
\nYoshii, T. et al. Brain atrophy in the visual cortex and thalamus induced by severe stress in
\nanimal model. Sci. Rep. 7, 12731, doi:10.1038\/s41598-017-12917-z (2017).<\/p>\n

Wei, P. et al. Processing of visually evoked innate fear by a non-canonical thalamic pathway. Nat Commun 6, 6756, doi:10.1038\/ncomms7756 (2015).<\/p>\n

Iyadurai, L. et al. Preventing intrusive memories after trauma via a brief intervention
\ninvolving Tetris computer game play in the emergency department: a proof-of-concept
\nrandomized controlled trial. Mol. Psychiatry 10.1038\/mp.2017.23, doi:10.1038\/mp.2017.23
\n(2017).<\/p>\n","protected":false},"excerpt":{"rendered":"

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