{"id":5640,"date":"2017-08-25T10:00:53","date_gmt":"2017-08-25T01:00:53","guid":{"rendered":"https:\/\/dev.academist-cf.com\/journal\/?p=5640"},"modified":"2018-10-03T19:26:40","modified_gmt":"2018-10-03T10:26:40","slug":"%e3%83%aa%e3%83%b3%e9%85%b8%e5%8c%96%e9%85%b5%e7%b4%a0%e3%81%8c%e7%a5%9e%e7%b5%8c%e7%b4%b0%e8%83%9e%e3%81%a7%e6%8b%85%e3%81%86%e6%a9%9f%e8%83%bd%e3%81%a8%e3%81%af%ef%bc%9f-%e6%a6%82%e6%97%a5","status":"publish","type":"post","link":"https:\/\/academist-cf.com\/journal\/?p=5640","title":{"rendered":"\u30ea\u30f3\u9178\u5316\u9175\u7d20\u304c\u795e\u7d4c\u7d30\u80de\u3067\u62c5\u3046\u6a5f\u80fd\u3068\u306f\uff1f \u2013 \u6982\u65e5\u30ea\u30ba\u30e0\u969c\u5bb3\u3068\u52a0\u9f62\u4f9d\u5b58\u7684\u306a\u904b\u52d5\u7570\u5e38\u3092\u793a\u3059\u5909\u7570\u30de\u30a6\u30b9"},"content":{"rendered":"

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\u30ea\u30f3\u9178\u5316\u9175\u7d20 MKK7\u3068\u306f\uff1f<\/h3>\n

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\"\"
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\"\"
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2.5\u30f6\u6708\u9f62\u3067\u306f\u6b63\u5e38\u30de\u30a6\u30b9\u3068MKK7\u6b20\u640d\u30de\u30a6\u30b9\u3067\u306f\u5f8c\u308d\u8db3\u306e\u958b\u304d\u306b\u5dee\u306f\u306a\u304b\u3063\u305f\u304c\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\uff088\u30f6\u6708\u4ee5\u964d\uff09MKK7 \u6b20\u640d\u30de\u30a6\u30b9\u3067\u306f\u5f8c\u308d\u8db3\u306e\u958b\u304d\u72ed\u304f\u306a\u308a\u300120\u30f6\u6708\u9f62\u3067\u306f\u5b8c\u5168\u306b\u5f8c\u308d\u8db3\u304c\u958b\u3051\u306a\u304f\u306a\u3063\u305f\u3002<\/figcaption><\/figure>\n

MKK7\u306e\u5f79\u5272<\/h3>\n

\u3067\u306f\u3001MKK7\u306f\u6210\u4f53\u306e\u795e\u7d4c\u7d30\u80de\u306b\u304a\u3044\u3066\u3001\u3069\u306e\u3088\u3046\u306a\u5f79\u5272\u3092\u6301\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f \u57f9\u990a\u7d30\u80de\u3092\u4f7f\u3063\u305f\u904e\u53bb\u306e\u7814\u7a76\u304b\u3089\u3001MKK7\u304c\u7d30\u80de\u5185\u306e\u6642\u8a08\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30ea\u30f3\u9178\u5316\u3057\u5b89\u5b9a\u6027\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u6642\u8a08\u306e\u5468\u671f\u3092\u9069\u5207\u306a\u9577\u3055\u306b\u5236\u5fa1\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001MKK7\u306e\u6b20\u640d\u306f\u3001\u795e\u7d4c\u7d30\u80de\u306e\u6642\u8a08\u5468\u671f\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u500b\u4f53\u306e\u6982\u65e5\u30ea\u30ba\u30e0\u3092\u5909\u5316\u3055\u305b\u305f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u904b\u52d5\u7570\u5e38\u3092\u793a\u3059\u8001\u9f62\u306eMKK7\u6b20\u640d\u30de\u30a6\u30b9\u306e\u810a\u9ac4\u3067\u306f\u8ef8\u7d22\u8f38\u9001\u306b\u95a2\u9023\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u84c4\u7a4d\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002MKK7\u304c\u8a98\u5c0e\u3059\u308b\u30b7\u30b0\u30ca\u30eb\u306f\u8ef8\u7d22\u8f38\u9001\u3092\u62c5\u3046\u30e2\u30fc\u30bf\u30fc\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308b\u30ad\u30cd\u30b7\u30f3\u306a\u3069\u3092\u30ea\u30f3\u9178\u5316\u3057\u3001\u305d\u306e\u6a5f\u80fd\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f93\u3063\u3066\u3001\u52a0\u9f62\u306b\u4f34\u3046\u904b\u52d5\u7570\u5e38\u306f\u3001MKK7\u306e\u6d3b\u6027\u306e\u4f4e\u4e0b\u306b\u3088\u3063\u3066\u795e\u7d4c\u7d30\u80de\u306e\u8ef8\u7d22\u8f38\u9001\u306b\u7570\u5e38\u3092\u304d\u305f\u3057\u3001\u8ef8\u7d22\u304c\u5909\u6027\u3057\u305f\u7d50\u679c\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u6700\u5f8c\u306b<\/h3>\n

\u6700\u8fd1\u3001\u7d71\u5408\u5931\u8abf\u75c7\u60a3\u8005\u306e\u4e2d\u306bMkk7\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u4e8b\u4f8b\u304c\u5831\u544a\u3055\u308c\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u307e\u3059\u3002\u6982\u65e5\u30ea\u30ba\u30e0\u969c\u5bb3\u3084\u52a0\u9f62\u4f9d\u5b58\u7684\u306a\u904b\u52d5\u80fd\u4f4e\u4e0b\u306b\u95a2\u3059\u308b\u4eca\u56de\u306e\u7814\u7a76\u304c\u3001\u4eca\u5f8c\u3001\u7cbe\u795e\u3084\u904b\u52d5\u306b\u969c\u5bb3\u3092\u6301\u3064\u30d2\u30c8\u75be\u60a3\u306e\u539f\u56e0\u89e3\u660e\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u3092\u671f\u5f85\u3057\u3001\u7814\u7a76\u3092\u7d9a\u3051\u3066\u3044\u304d\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u53c2\u8003\u6587\u732e<\/strong>
\nTokiwa Yamasaki1, Norie Deki-Arima1, et al., (2017) Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.\u00a0Scientific Reports\u00a07, 7348. (1Contributed equally)<\/p>\n","protected":false},"excerpt":{"rendered":"

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