{"id":2417,"date":"2016-11-04T10:00:24","date_gmt":"2016-11-04T01:00:24","guid":{"rendered":"https:\/\/dev.academist-cf.com\/journal\/?p=2417"},"modified":"2017-02-15T12:19:07","modified_gmt":"2017-02-15T03:19:07","slug":"%e3%80%90%e9%80%a3%e8%bc%89%e3%80%91%e8%84%b3%e6%9c%9b%e9%81%a0%e9%8f%a1%ef%bc%9abiology-5-0%e3%81%a7%e8%84%b3%e3%81%ab%e6%8c%91%e3%82%80%ef%bc%882%ef%bc%89","status":"publish","type":"post","link":"https:\/\/academist-cf.com\/journal\/?p=2417","title":{"rendered":"\u3010\u9023\u8f09\u3011\u8133\u671b\u9060\u93e1\uff1aBiology 5.0\u3067\u8133\u306b\u6311\u3080\uff082\uff09"},"content":{"rendered":"<p><a href=\"https:\/\/dev.academist-cf.com\/journal\/?s=Biology+5.0\">* \u9023\u8f09\u76ee\u6b21\u306f\u3053\u3061\u3089<\/a><\/p>\n<p>\u30ac\u30ea\u30ec\u30aa\u30fb\u30ac\u30ea\u30ec\u30a4\uff081564-1642\uff09\u306f\u3001\u521d\u3081\u3066\u671b\u9060\u93e1\u3092\u4f7f\u3063\u305f\u5929\u4f53\u89b3\u6e2c\u3092\u3057\u3001\u9855\u5fae\u93e1\u3092\u4f7f\u3063\u3066\u6606\u866b\u306e\u8907\u773c\u3092\u89b3\u5bdf\u3057\u307e\u3057\u305f\u3002\u30ac\u30ea\u30ec\u30aa\u306f\u3001\u30d4\u30b5\u306e\u659c\u5854\u306e\u6709\u540d\u306a\u843d\u4e0b\u5b9f\u9a13\u3067\u77e5\u3089\u308c\u308b\u3088\u3046\u306b\u3001\u5b9f\u9a13\u7269\u7406\u5b66\u306e\u5275\u59cb\u8005\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30ac\u30ea\u30ec\u30aa\u306e\u7236\u3067\u3042\u308b\u30f4\u30a3\u30f3\u30c1\u30a7\u30f3\u30c4\u30a9\u30fb\u30ac\u30ea\u30ec\u30a4\uff081520-1591\uff09\u306f\u3001\u6b74\u53f2\u306b\u6b8b\u308b\u97f3\u697d\u5bb6\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u97f3\u697d\u7406\u8ad6\u306b\u6570\u5b66\u7684\u306a\u65b9\u6cd5\u3092\u5c0e\u5165\u3057\u3001\u606f\u5b50\u306e\u5fd7\u5411\u306b\u3082\u591a\u5927\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u305f\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u9855\u5fae\u93e1\u3067\u690d\u7269\u3092\u89b3\u5bdf\u3059\u308b\u3053\u3068\u3067 \u300cCell\uff08\u7d30\u80de\uff09\u300d\u3068\u3044\u3046\u6982\u5ff5\u3092\u63d0\u5531\u3057\u305f\u30ed\u30d0\u30fc\u30c8\u30fb\u30d5\u30c3\u30af\uff081635-1703\uff09\u306f\u3001\u5f3e\u6027\u306b\u95a2\u3059\u308b\u6cd5\u5247\u3067\u3082\u6709\u540d\u3067\u3059\u3002\u3053\u306e\u6642\u4ee3\u306f\u3001\u6570\u5b66\u3001\u7269\u7406\u5b66\u3001\u5929\u6587\u5b66\u3001\u5316\u5b66\u3001\u30d0\u30a4\u30aa\u3001\u5de5\u5b66\u3001\u533b\u5b66\u3001\u305d\u3057\u3066\u97f3\u697d\u3082\u82b8\u8853\u3082\u5bc6\u63a5\u306b\u300c\u878d\u5408\u300d\u3057\u3066\u3044\u305f\u306e\u3067\u3059\u3002<\/p>\n<p>\u3068\u3053\u308d\u304c\u305d\u306e\u5f8c\u3001\u305d\u308c\u305e\u308c\u306e\u5206\u91ce\u304c\u5206\u96e2\u3057\u3066\u3044\u304d\u307e\u3057\u305f\u300220\u4e16\u7d00\u5f8c\u534a\u306e\u79d1\u5b66\u7814\u7a76\u306f\u3001\u3053\u306e\u3088\u3046\u306a\u5206\u91ce\u5225\u306e\u7814\u7a76\u304c\u79d1\u5b66\u7814\u7a76\u306e\u5178\u578b\u3068\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002\u305d\u3053\u3067\u8fd1\u5e74\u3001\u5206\u91ce\u878d\u5408\u3001\u5206\u91ce\u6a2a\u65ad\uff08Interdisciplinary\uff09\u3001\u3055\u3089\u306b\u306f\u5206\u91ce\u969c\u58c1\u306e\u7834\u58ca\u578b\uff08Anti-Disciplinary\uff09\u3068\u3044\u3046\u3053\u3068\u304c\u3001\u3055\u307e\u3056\u307e\u306a\u5834\u9762\u3067\u5f37\u8abf\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u304d\u3066\u3044\u308b\u306e\u306f\u591a\u304f\u306e\u65b9\u304c\u611f\u3058\u3066\u3044\u308b\u3053\u3068\u3067\u3057\u3087\u3046\u3002<a href=\"https:\/\/dev.academist-cf.com\/journal\/?p=2363\">\u524d\u56de<\/a>\u8aac\u660e\u3057\u305fBiology5.0\u3067\u306f\u3001\u3053\u306e\u30de\u30a4\u30f3\u30c9\u30bb\u30c3\u30c8\u304c\u6c7a\u5b9a\u7684\u306b\u5927\u5207\u306b\u306a\u3063\u3066\u304f\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<figure id=\"attachment_2506\" aria-describedby=\"caption-attachment-2506\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2506\" src=\"https:\/\/dev.academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/Figrue1-my.jpg\" alt=\"figrue1-my\" width=\"500\" height=\"289\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/Figrue1-my.jpg 676w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/Figrue1-my-300x174.jpg 300w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-2506\" class=\"wp-caption-text\">\u30c7\u30a3\u30b7\u30d7\u30ea\u30f3\u306e\u58c1\u3092\u58ca\u305d\u3046<\/figcaption><\/figure>\n<p>\u79d1\u5b66\u7814\u7a76\u306e\u73fe\u72b6\u3067\u306f\u3001\u4f9d\u7136\u3068\u3057\u3066\u5206\u91ce\u306e\u67a0\u306b\u3053\u3060\u308f\u3063\u305f\u7814\u7a76\u304c\u76db\u3093\u3067\u3042\u308b\u3068\u611f\u3058\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u7814\u7a76\u5ba4\u3001\u8b1b\u5ea7\u3001\u5b66\u79d1\u3001\u90e8\u9580\u3001\u5b66\u90e8\u3001\u5927\u5b66\u3001\u7814\u7a76\u6240\u3001\u5b66\u4f1a\u306a\u3069\u3001\u3044\u308d\u3044\u308d\u306a\u7d44\u7e54\u304c\u58c1\u3092\u4f5c\u3063\u3066\u3044\u3066\u3001\u305d\u3046\u3044\u3046\u300c\u30c7\u30a3\u30b7\u30d7\u30ea\u30f3\u306e\u58c1\u300d\u3092\u58ca\u305b\u306a\u3044\u3088\u3046\u306a\u4ed5\u7d44\u307f\u306b\u306a\u3063\u3066\u3044\u308b\u304b\u3089\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u8a00\u3046\u307e\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u300cInterdisciplinary\u300d\u3068\u304b\u3001\u300cAnti-disciplinary\u300d\u3068\u3044\u3046\u306e\u306f\u3001\u305d\u3046\u3044\u3046\u58c1\u3092\u306a\u304f\u305d\u3046\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u7279\u306b\u3001\u65e5\u672c\u306e\u79d1\u5b66\u7814\u7a76\u306e\u73fe\u5834\u3067\u306f\u3001\u3053\u306e\u7d44\u7e54\u306e\u5b58\u5728\u306b\u3088\u308b\u300c\u30c7\u30a3\u30b7\u30d7\u30ea\u30f3\u306e\u58c1\u300d\u304c\u5805\u56fa\u3067\u3042\u308b\u3068\u3044\u3046\u5370\u8c61\u3092\u53d7\u3051\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u6700\u8fd1\u306e\u30a2\u30ab\u30c7\u30df\u30a2\u306e\u53b3\u3057\u3044\u7af6\u4e89\u7684\u306a\u74b0\u5883\u3067\u306f\u3001\u500b\u3005\u306e\u7814\u7a76\u8005\u3092\u57cb\u6ca1\u3055\u305b\u308b\u3088\u3046\u306a\u30bf\u30a4\u30d7\u306e\u5171\u540c\u7814\u7a76\u3092\u963b\u5bb3\u3057\u3084\u3059\u304f\u306a\u3063\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3001\u3068\u3044\u3046\u61f8\u5ff5\u304c\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u30d0\u30a4\u30aa\u7cfb\u3067\u3082\u5171\u540c\u7814\u7a76\u3068\u3044\u3046\u306e\u306f\u3001\u3057\u3070\u3057\u3070\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3068\u3053\u308d\u304c\u5b9f\u969b\u3001\u5206\u91ce\u878d\u5408\u578b\u306e\u5171\u540c\u7814\u7a76\u3068\u3044\u3046\u306e\u306f\u305d\u308c\u307b\u3069\u591a\u304f\u306a\u3044\u306e\u3067\u3059\u3002\u307b\u3068\u3093\u3069\u306e\u5171\u540c\u7814\u7a76\u3068\u3044\u3046\u306e\u306f\u3001\u4eba\u624b\u304c\u591a\u3044\u65b9\u304c\u901f\u304f\u7814\u7a76\u304c\u9032\u3080\u3068\u3044\u3046\u7a2e\u985e\u306e\u3082\u306e\u3067\u3059\u3002\u4ed5\u4e8b\u3092\u9811\u5f35\u308c\u3070\u3001\u81ea\u5206\u4e00\u4eba\u3067\u3082\u3067\u304d\u308b\u306e\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3001\u4ed6\u306e\u4eba\u306b\u3084\u3063\u3066\u3082\u3089\u3046\u3068\u3044\u3046\u611f\u3058\u3067\u3059\u3002\u3053\u3046\u3044\u3046\u306e\u306f\u3001\u5206\u91ce\u878d\u5408\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u4eca\u56de\u306f\u3001\u79c1\u304c\u6700\u8fd1\u4f53\u9a13\u3057\u305f\u3072\u3068\u3064\u306e\u5206\u91ce\u878d\u5408\u578b\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u7d39\u4ecb\u3057\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<h3>\u30b3\u30cd\u30af\u30c8\u30fc\u30e0\u3068\u5316\u5b66\u89aa\u548c\u8aac<\/h3>\n<p><a href=\"https:\/\/dev.academist-cf.com\/journal\/?p=2363\">\u524d\u56de<\/a>\u8aac\u660e\u3057\u305f\u3088\u3046\u306b\u3001\u30b3\u30cd\u30af\u30c8\u30fc\u30e0\u3068\u3044\u3046\u306e\u306f\u3001 \u8133\u795e\u7d4c\u7cfb\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u304c\u4f5c\u3063\u3066\u3044\u308b\u795e\u7d4c\u56de\u8def\u306e\u300c\u307e\u3068\u3081\u3066\u3059\u3079\u3066\u300d\u3092\u610f\u5473\u3059\u308b\u6982\u5ff5\u3067\u3059\u3002\u30cb\u30e5\u30fc\u30ed\u30f3\u540c\u58eb\u304c\u63a5\u7d9a\u3057\u3066\u3044\u308b\u306e\u306f\u3001\u300c\u30b7\u30ca\u30d7\u30b9\u300d\u3068\u3044\u3046\u69cb\u9020\u3067\u3059\u3002\u30b7\u30ca\u30d7\u30b9\u306f\u3001\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\uff08\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u3001\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u306a\u3069\uff09\u3092\u653e\u51fa\u3059\u308b\u9846\u7c92\u3092\u6301\u3064\u30b7\u30ca\u30d7\u30b9\u524d\u90e8\u306e\u7d30\u80de\u819c\u3068\u3001\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u53d7\u5bb9\u4f53\u3092\u6301\u3064\u30b7\u30ca\u30d7\u30b9\u5f8c\u90e8\u306e\u7d30\u80de\u819c\u304c\u63a5\u7740\u3057\u305f\u69cb\u9020\u3092\u3057\u3066\u3044\u307e\u3059\u3002\u63a5\u7740\u69cb\u9020\u3067\u3059\u304b\u3089\u3001\u305d\u308c\u3092\u3064\u306a\u3044\u3067\u3044\u308b\u63a5\u7740\u5206\u5b50\u3068\u3044\u3046\u306e\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u308f\u3051\u3067\u3059\u3002<\/p>\n<p>\u795e\u7d4c\u56de\u8def\u3067\u306f\u3001\u30cb\u30e5\u30fc\u30ed\u30f3\u540c\u58eb\u306e\u63a5\u7d9a\u306e\u95a2\u4fc2\u304c\u3001\u3061\u3087\u3046\u3069\u9375\u3068\u9375\u7a74\u306e\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u308b\u305f\u3081\u306b\u3001\u304d\u3061\u3093\u3068\u795e\u7d4c\u56de\u8def\u304c\u3067\u304d\u3042\u304c\u308a\u3001\u7dad\u6301\u3055\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u8aac\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u534a\u4e16\u7d00\u307b\u3069\u524d\u3001\u30ed\u30b8\u30e3\u30fc\u30fb\u30b9\u30da\u30fc\u30ea\uff081913-1994\u30011991\u5e74\u30ce\u30fc\u30d9\u30eb\u751f\u7406\u5b66\u30fb\u533b\u5b66\u8cde\uff09\u306b\u3088\u3063\u3066\u5531\u3048\u3089\u308c\u305f\u8aac\u3067\u300c\u5316\u5b66\u89aa\u548c\u8aac Chemoaffinity theory\u300d\u3068\u3044\u3044\u307e\u3059\u3002\u76f4\u89b3\u7684\u306b\u306f\u3068\u3066\u3082\u30b7\u30f3\u30d7\u30eb\u3067\u3001\u305d\u308c\u305e\u308c\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u8868\u9762\u306b\u9375\u3001\u305d\u308c\u306b\u63a5\u7d9a\u3059\u308b\u5225\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u9375\u7a74\u304c\u3042\u308a\u3001\u4e21\u8005\u306e\u5f62\u304c\u3074\u3063\u305f\u308a\u540c\u3058\u306a\u306e\u3067\u3001\u6b63\u3057\u304f\u3064\u306a\u304c\u308b\u3068\u3044\u3046\u30a2\u30a4\u30c7\u30a2\u3067\u3059\u3002\u3053\u306e20\u5e74\u307b\u3069\u306e\u9593\u306b\u3001\u9375\u3068\u9375\u7a74\u306e\u5f79\u5272\u3092\u3059\u308b\u5206\u5b50\u3068\u3044\u3046\u306e\u304c\u5b9f\u969b\u306b\u308f\u304b\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002<\/p>\n<figure id=\"attachment_2419\" aria-describedby=\"caption-attachment-2419\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2419\" src=\"https:\/\/dev.academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig2-chemoaffinity.jpeg\" width=\"500\" height=\"166\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig2-chemoaffinity.jpeg 700w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig2-chemoaffinity-300x100.jpeg 300w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-2419\" class=\"wp-caption-text\">\u5316\u5b66\u89aa\u548c\u8aac\uff1a\u30cb\u30e5\u30fc\u30ed\u30f3\u540c\u58eb\u304c\u6b63\u3057\u304f\u3064\u306a\u304c\u308b\u6642\u306e\u9375\u3068\u9375\u7a74\uff08Sanes &amp; Yamagata, 2009\u3088\u308a\uff09\u3002<\/figcaption><\/figure>\n<h3>\u795e\u7d4c\u56de\u8def\u306e\u76f8\u68d2\u3092\u3064\u306a\u3050Sidekick<\/h3>\n<p>\u9375\u3068\u9375\u7a74\u306e\u3088\u3046\u306a\u5316\u5b66\u89aa\u548c\u3092\u62c5\u3046\u5206\u5b50\u306b\u3001Sidekick1\uff08Sdk1\uff09\u304a\u3088\u3073Sidekick2\uff08Sdk2\uff09\u3068\u3044\u3046\u3088\u304f\u4f3c\u305f2\u7a2e\u985e\u306e\u7d30\u80de\u8868\u9762\u5206\u5b50\u304c\u3042\u308a\u307e\u3059\u3002Sidekick\u306f\u300c\u76f8\u68d2\u300d\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u79c1\u305f\u3061\u306f2002\u5e74\u306b\u3001\u30cb\u30ef\u30c8\u30ea\u306e\u7db2\u819c\u3067\u3001\u7570\u306a\u308b\u7a2e\u985e\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u3067\u7279\u7570\u7684\u306b\u767a\u73fe\u3057\u3001\u9375\u3068\u9375\u7a74\u306e\u5f79\u5272\u3092\u3059\u308b\u7d30\u80de\u8868\u9762\u5206\u5b50\u3092\u767a\u898b\u3057\u307e\u3057\u305f\uff08\u8a73\u7d30\u306f<a href=\"http:\/\/first.lifesciencedb.jp\/tags\/%E7%B6%B2%E8%86%9C\">\u3053\u3061\u3089<\/a>\uff09\u3002<\/p>\n<p>\u3053\u306e\u5206\u5b50\u306e\u6027\u8cea\u3067\u3042\u308b\u9375\u3068\u9375\u7a74\u306e\u5316\u5b66\u89aa\u548c\u306e\u95a2\u4fc2\u306f\u660e\u78ba\u3067\u3001Sdk1\u306fSdk1\u3068\u3001Sdk2\u306fSdk2\u3068\u306e\u307f\u7d50\u5408\u3057\u3001Sdk1\u3068Sdk2\u3068\u306f\u7d50\u5408\u3057\u306a\u3044\u30db\u30e2\u30d5\u30a3\u30ea\u30c3\u30af\u306a\u6027\u8cea\u3092\u6301\u3061\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u9375\u3068\u9375\u7a74\u304c\u540c\u3058\u5206\u5b50\u306b\u306a\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u30012\u3064\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u304c\u540c\u3058Sdk\u3092\u767a\u73fe\u3057\u3066\u3044\u308c\u3070\uff0c\u795e\u7d4c\u7a81\u8d77\u3069\u3046\u3057\u304c\u30db\u30e2\u30d5\u30a3\u30ea\u30c3\u30af\u306a\u7d50\u5408\u3092\u8d77\u3053\u3057\u3001\u56de\u8def\u306e\u63a5\u7d9a\u306b\u3044\u305f\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<figure id=\"attachment_2507\" aria-describedby=\"caption-attachment-2507\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2507\" src=\"https:\/\/dev.academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/fignew.png\" width=\"500\" height=\"205\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/fignew.png 933w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/fignew-300x123.png 300w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/11\/fignew-768x315.png 768w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-2507\" class=\"wp-caption-text\">Sdk1\u306fSdk1\u3068\u3001Sdk2\u306fSdk2\u3068\u89aa\u548c\u529b\u3092\u6301\u3064<\/figcaption><\/figure>\n<p>\u79c1\u305f\u3061\u306f2015\u5e74\u306b\u3001\u30de\u30a6\u30b9\u306e\u7db2\u819c\u3067\u3001\u7db2\u819c\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u300cW3B\u300d\u3068\u305d\u306e\u795e\u7d4c\u7d50\u5408\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u3067\u3042\u308b\u30cb\u30e5\u30fc\u30ed\u30f3\u300cVG3\u300d\u306b\u304a\u3044\u3066\u3001Sdk2\u304c\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002Sdk2\u304c\u3053\u306e2\u7a2e\u985e\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u304c\u4f5c\u3063\u3066\u3044\u308b\u795e\u7d4c\u56de\u8def\u3092\u898f\u5b9a\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001Sdk2\u907a\u4f1d\u5b50\u3092\u767a\u73fe\u3067\u304d\u306a\u304f\u306a\u308b\u3088\u3046\u306b\u3057\u305f\u30de\u30a6\u30b9\u3067\u306f\u30012\u7a2e\u985e\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u9593\u306e\u7d50\u5408\u306b\u969c\u5bb3\u304c\u8d77\u3053\u308b\u3053\u3068\u3092\u3001\u5149\u907a\u4f1d\u5b66\u306e\u624b\u6cd5\u306a\u3069\u306b\u3088\u308a\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u5206\u5b50\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u306f\u3001\u79c1\u305f\u3061\u3082\u672a\u3060Biology3.0\u306e\u4e16\u754c\u3092\u5f98\u5f8a\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u5c06\u6765\u7684\u306b\u306fBiology5.0\u306e\u4e16\u754c\u306b\u306a\u308b\u3088\u3046\u306b\u3057\u305f\u3044\u3068\u8003\u3048\u3001\u73fe\u5728\u3082\u7814\u7a76\u3092\u7d9a\u3051\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<h3>\u5206\u91ce\u878d\u5408\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u308f\u304b\u3063\u305f\u5316\u5b66\u89aa\u548c\u529b\u3092\u9ad8\u3081\u308b\u65b0\u3057\u3044\u30e1\u30ab\u30cb\u30ba\u30e0<\/h3>\n<p>\u6700\u8fd1\u3001\u30cb\u30e5\u30fc\u30e8\u30fc\u30af\u306e\u30b3\u30ed\u30f3\u30d3\u30a2\u5927\u5b66\u306e\u69cb\u9020\u751f\u7269\u5b66\u8005\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u3001\u7d30\u80de\u8868\u9762\u5206\u5b50\u306e\u982d\u5074\u306b\u3042\u308b\u300c\u99ac\u8e44\uff08\u3046\u307e\u306e\u3072\u3065\u3081\uff09\u300d\u306e\u5f62\u3092\u3057\u305f\u90e8\u5206\u306e\u7acb\u4f53\u69cb\u9020\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002\u4e0a\u56f3\u3067\u756a\u53f7\u3092\u4ed8\u3051\u305f6\u3064\u306e\u6955\u5186\u5f62\u306e\u69cb\u9020\u304c\u4e38\u307e\u308b\u3053\u3068\u3067\u3001\u99ac\u8e44\u5f62\u306b\u306a\u308a\u307e\u3059\u3002\u99ac\u8e44\u5f62\u306e\u90e8\u5206\u306f\u3001\u8840\u6db2\u4e2d\u306b\u3042\u308b\u6297\u4f53\u5206\u5b50\u3067\u3042\u308b\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u3068\u69cb\u9020\u304c\u3088\u304f\u4f3c\u3066\u3044\u308b\u306e\u3067\u3001\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u30c9\u30e1\u30a4\u30f3\uff08Immunoglobulin, Ig\uff09\u30c9\u30e1\u30a4\u30f3\u3068\u547c\u3070\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u79c1\u305f\u3061\u306f\u3001\u305d\u306e\u90e8\u5206\u306eSdk1\u3068Sdk2\u306e\u7d50\u6676\u69cb\u9020\u3092\u89e3\u304f\u3053\u3068\u306b\u6210\u529f\u3057\u3001\u305d\u306e\u69cb\u9020\u304b\u3089\u30db\u30e2\u30d5\u30a3\u30ea\u30c3\u30af\u306a\u7d50\u5408\u304c\u3069\u306e\u3088\u3046\u306b\u751f\u3058\u308b\u306e\u304b\u3068\u3044\u3046\u3053\u3068\u3092\u63a8\u6e2c\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u7814\u7a76\u306f\u3001\u5171\u540c\u7814\u7a76\u8005\u3067\u3042\u308b\u30b3\u30ed\u30f3\u30d3\u30a2\u5927\u5b66\u306e\u69cb\u9020\u751f\u7269\u5b66\u8005\uff08Kerry Goodman\u535a\u58eb\u3001Barry Honig\u535a\u58eb\u3001Larry Shapiro\u535a\u58eb\uff09\u304cX\u7dda\u7d50\u6676\u69cb\u9020\u89e3\u6790\u3092\u3001\u79c1\u304c\u7d30\u80de\u3092\u4f7f\u3063\u305f\u5b9f\u9a13\u3092\u62c5\u5f53\u3057\u307e\u3057\u305f\u3002\u79c1\u81ea\u8eab\u3001\u5b66\u90e8\u751f\u6642\u4ee3\u306b\u751f\u5316\u5b66\u306e\u7814\u7a76\u3092\u3084\u3063\u3066\u3044\u307e\u3057\u305f\u306e\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7d50\u6676\u4f5c\u88fd\u306b\u3082\u5c11\u3057\u99b4\u67d3\u307f\u306f\u3042\u308a\u307e\u3057\u305f\u304c\u3001X\u7dda\u7d50\u6676\u69cb\u9020\u89e3\u6790\u306e\u7d4c\u9a13\u306f\u5168\u304f\u3042\u308a\u307e\u305b\u3093\u306e\u3067\u3001\u672c\u7814\u7a76\u306f\u5168\u304f\u7570\u306a\u308b\u5206\u91ce\u304c\u878d\u5408\u3057\u305f\u7814\u7a76\u306e\u5178\u578b\u3067\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u30db\u30e2\u30d5\u30a3\u30ea\u30c3\u30af\u306a\u7d50\u5408\u3092\u3059\u308bIg\u30c9\u30e1\u30a4\u30f3\u3092\u6301\u3063\u305f\u8a8d\u8b58\u5206\u5b50\u306f\u6570\u591a\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u9a5a\u3044\u305f\u3053\u3068\u306b\u3001Sdk\u306e\u69cb\u9020\u304b\u3089\u63a8\u5b9a\u3055\u308c\u305f\u30db\u30e2\u30d5\u30a3\u30ea\u30c3\u30af\u306a\u5206\u5b50\u9593\u76f8\u4e92\u4f5c\u7528\u306f\u3001\u3053\u308c\u307e\u3067\u89e3\u660e\u3055\u308c\u3066\u304d\u305f\u985e\u4f3c\u5206\u5b50\u306e\u69d8\u76f8\u3068\u304b\u306a\u308a\u9055\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u69cb\u9020\u306e\u4e2d\u3067\u3001\u3069\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u304c\u3053\u306e\u30db\u30e2\u30d5\u30a3\u30ea\u30c3\u30af\u306a\u89aa\u548c\u6027\u306b\u5927\u5207\u304b\u3068\u3044\u3046\u306e\u3082\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u7279\u5b9a\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u3092\u5225\u306e\u30a2\u30df\u30ce\u9178\u306b\u5909\u7570\u3059\u308b\u3068\u3001\u5206\u5b50\u5168\u4f53\u3092\u7d30\u80de\u306b\u767a\u73fe\u3055\u305b\u305f\u6642\u306b\u89b3\u5bdf\u3055\u308c\u308b\u7d30\u80de\u63a5\u7740\u6d3b\u6027\u3082\u6d88\u5931\u3057\u307e\u3057\u305f\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u3053\u306e\u6d3b\u6027\u3092\u5931\u3063\u305f\u5909\u7570\u5206\u5b50\u306f\u3001\u7570\u306a\u308b\u7d30\u80de\u9593\u3067\u306e\u7d30\u80de\u63a5\u7740\u3092\u3057\u306a\u304f\u306a\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u3072\u3068\u3064\u306e\u7d30\u80de\u306b\u767a\u73fe\u3055\u305b\u305f\u5834\u5408\u3082\u3001\u6b63\u5e38\u306a\u3082\u306e\u3068\u306f\u9055\u3046\u6319\u52d5\u3092\u793a\u3059\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3064\u307e\u308a\u3001\u4e0b\u56f3\u306e\u3088\u3046\u306b\u3001\u672c\u6765\u3001\u7d30\u80de\u63a5\u7740\u3084\u8a8d\u8b58\u306e\u305f\u3081\u306b\u7570\u306a\u308b\u7d30\u80de\u8868\u9762\u306b\u767a\u73fe\u3057\u305f\u5834\u5408\u306b\u8d77\u3053\u308b\u5206\u5b50\u9593\u76f8\u4e92\u4f5c\u7528\uff08trans\u76f8\u4e92\u4f5c\u7528\uff1d\u7d30\u80de\u63a5\u7740\uff09\u304c\u3001\u540c\u3058\u7d30\u80de\u8868\u9762\u4e0a\u3067\u3082\u8d77\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\uff08cis\u76f8\u4e92\u4f5c\u7528\uff09\u3002<\/p>\n<figure id=\"attachment_2421\" aria-describedby=\"caption-attachment-2421\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2421\" src=\"https:\/\/dev.academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig4-sdkmodel-1024x415.jpg\" alt=\"fig4-sdkmodel\" width=\"500\" height=\"203\" srcset=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig4-sdkmodel.jpg 1024w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig4-sdkmodel-300x122.jpg 300w, https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2016\/10\/Fig4-sdkmodel-768x311.jpg 768w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-2421\" class=\"wp-caption-text\">\u7d30\u80de\u8868\u9762\u4e0a\u306eSdk\u5206\u5b50\u306e\u3088\u308b\u5316\u5b66\u89aa\u548c\u306e\u7279\u7570\u6027\u3092\u9ad8\u3081\u308b\u65b0\u30e2\u30c7\u30eb\uff08Goodman et al, 2016\uff09<\/figcaption><\/figure>\n<p>\u3064\u307e\u308a\u3001Sdk1\u306e\u5834\u5408\u3001cis\u76f8\u4e92\u4f5c\u7528\u3068trans\u76f8\u4e92\u4f5c\u7528\u3092\u540c\u3058\u69cb\u9020\u3092\u4f7f\u3063\u3066\u884c\u3063\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002\u305d\u306e\u7d50\u679c\u3001trans\u76f8\u4e92\u4f5c\u7528\uff08\u7d30\u80de\u63a5\u7740\uff09\u304c\u8d77\u3063\u3066\u3044\u306a\u3044\u6642\u306b\u306f\u3001\u540c\u3058\u7d30\u80de\u8868\u9762\u4e0a\u3067cis\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u3067\u3001\u304b\u3059\u304b\u306b\u898b\u3089\u308c\u308bSdk2\u3068\u306e\u7d50\u5408\u3092\u9632\u6b62\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3057\u3066\u3001cis\u3068trans\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u7d30\u80de\u8868\u9762\u4e0a\u3067\u7af6\u5408\u7684\u306a\u95a2\u4fc2\u306b\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u3067\u3001\u30b7\u30ca\u30d7\u30b9\u304c\u3067\u304d\u308b\u6642\u306e\u9375\u3068\u9375\u7a74\u306e\u7279\u7570\u6027\u3092\u66f4\u306b\u5f37\u3081\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3001\u3068\u3044\u3046\u65b0\u3057\u3044\u30e2\u30c7\u30eb\u3092\u63d0\u5531\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/dev.academist-cf.com\/journal\/?p=2631\">\u7b2c3\u56de\u3078\u7d9a\u304f<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<ul>\n<li><a href=\"http:\/\/first.lifesciencedb.jp\/tags\/%E7%B6%B2%E8%86%9C\">\u30b7\u30ca\u30d7\u30b9\u63a5\u7740\u5206\u5b50Sdk2\u306f\u7db2\u819c\u306b\u304a\u3044\u3066\u7269\u4f53\u306e\u52d5\u304d\u3092\u691c\u51fa\u3059\u308b\u795e\u7d4c\u56de\u8def\u306e\u5f62\u6210\u306b\u6a5f\u80fd\u3059\u308b<\/a>\uff082015\u5e74\uff09\u5c71\u5f62\u65b9\u4eba \u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u65b0\u7740\u8ad6\u6587\u30ec\u30d3\u30e5\u30fc<\/li>\n<li>Sanes JR, Yamagata M. (2009) Annu Rev Cell Dev Biol. 25:161-195. Many paths to synaptic specificity.\u00a0Goodman KM, Yamagata M, Jin X, Mannepalli S, Katsamba PS, Ahls\u00e9n G, Sergeeva AP, Honig B,Sanes JR, Shapiro L.(2016) Elife. 2016 Sep 19;5. pii: e19058.\u00a0<a href=\"https:\/\/elifesciences.org\/content\/5\/e19058\">Molecular basis of sidekick-mediated cell-cell adhesion and specificity<\/a>.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>* \u9023\u8f09\u76ee\u6b21\u306f\u3053\u3061\u3089 \u30ac\u30ea\u30ec\u30aa\u30fb\u30ac\u30ea\u30ec\u30a4\uff081564-1642\uff09\u306f\u3001\u521d\u3081\u3066\u671b\u9060\u93e1\u3092\u4f7f\u3063\u305f\u5929\u4f53\u89b3\u6e2c\u3092\u3057\u3001\u9855\u5fae\u93e1\u3092\u4f7f\u3063\u3066\u6606\u866b\u306e\u8907\u773c\u3092\u89b3\u5bdf\u3057\u307e\u3057\u305f\u3002\u30ac\u30ea\u30ec\u30aa\u306f\u3001\u30d4\u30b5\u306e\u659c\u5854\u306e\u6709\u540d\u306a\u843d\u4e0b\u5b9f\u9a13\u3067\u77e5\u3089\u308c\u308b\u3088\u3046\u306b\u3001\u5b9f\u9a13 [&hellip;]<\/p>\n","protected":false},"author":49,"featured_media":2418,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[3],"tags":[15,24],"class_list":["post-2417","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-outcome","tag-biology","tag-24","has_thumb"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2417"}],"version-history":[{"count":0,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2417\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/media\/2418"}],"wp:attachment":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2417"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2417"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}