{"id":17121,"date":"2024-11-04T16:25:35","date_gmt":"2024-11-04T07:25:35","guid":{"rendered":"https:\/\/academist-cf.com\/journal\/?p=17121"},"modified":"2024-11-04T16:25:35","modified_gmt":"2024-11-04T07:25:35","slug":"%e9%ab%98%e9%bd%a2%e6%9c%9f%e3%81%ab%e3%83%80%e3%83%b3%e3%82%b9%e3%82%92%e5%a7%8b%e3%82%81%e3%82%8b%e3%81%93%e3%81%a8%e3%81%ae%e5%8a%b9%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/academist-cf.com\/journal\/?p=17121","title":{"rendered":"\u9ad8\u9f62\u671f\u306b\u30c0\u30f3\u30b9\u3092\u59cb\u3081\u308b\u3053\u3068\u306e\u52b9\u679c"},"content":{"rendered":"<h3>\u306f\u3058\u3081\u306b<\/h3>\n<p>\u4eba\u751f100\u5e74\u6642\u4ee3\u3068\u3044\u308f\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u500b\u4eba\u5dee\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u81ea\u7acb\u3057\u3066\u904e\u3054\u3059\u3053\u3068\u306e\u3067\u304d\u308b\u300c\u5065\u5eb7\u5bff\u547d\u300d\u306e\u65e5\u672c\u4eba\u306e\u5e73\u5747\u306f\u3001\u5973\u6027\u304c75\u6b73\u3001\u7537\u6027\u304c72\u6b73\u7a0b\u5ea6\u3067\u3042\u308a\u3001\u6669\u5e74\u306b\u306f\u65e5\u5e38\u751f\u6d3b\u3067\u30b5\u30dd\u30fc\u30c8\u306e\u5fc5\u8981\u306a\u4eba\u304c\u591a\u304f\u306a\u308a\u307e\u3059\u3002\u4ecb\u8b77\u304c\u5fc5\u8981\u306b\u306a\u308b\u7406\u7531\u306e\u4e0a\u4f4d\u306b\u306f\u8a8d\u77e5\u75c7\u304c\u3042\u308a\u3001\u5973\u6027\u3067\u306f\u30c8\u30c3\u30d7\u306e\u7406\u7531\u3067\u3059\u3002\u8a8d\u77e5\u75c7\u306b\u306a\u308a\u306b\u304f\u3044\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u5fc3\u304c\u3051\u305f\u3044\u3082\u306e\u3067\u3059\u304c\u3001\u3069\u3093\u306a\u8da3\u5473\u3092\u3082\u3064\u3068\u826f\u3044\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n<p>75\u6b73\u4ee5\u4e0a\u3092\u5bfe\u8c61\u306b\u3069\u3093\u306a\u4f59\u6687\u6d3b\u52d5\u304c\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3092\u6291\u3048\u308b\u304b\u3092\u8abf\u3079\u305f\u89b3\u5bdf\u7684\u306a\u75ab\u5b66\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u30c0\u30f3\u30b9\u306f\u697d\u5668\u6f14\u594f\u306a\u3069\u3068\u4e26\u3073\u3001\u629c\u304d\u3093\u51fa\u3066\u30ea\u30b9\u30af\u4f4e\u6e1b\u52b9\u679c\u304c\u9ad8\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059 [1] 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id=\"attachment_17124\" aria-describedby=\"caption-attachment-17124\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-17124 size-full\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2024\/10\/Fig1_\u753b\u50cf001-01\u30bf\u3099\u30f3\u30b9-e1729922145668.jpg\" alt=\"\" width=\"600\" height=\"338\" \/><figcaption id=\"caption-attachment-17124\" class=\"wp-caption-text\">\u56f31 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id=\"attachment_17125\" aria-describedby=\"caption-attachment-17125\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-17125 size-full\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2024\/10\/Fig2_apathy-e1730447444416.jpg\" alt=\"\" width=\"300\" height=\"378\" \/><figcaption id=\"caption-attachment-17125\" class=\"wp-caption-text\">\u56f32\u3000\u30a2\u30d1\u30b7\u30fc\u306e\u5f97\u70b9\u5909\u5316\uff1a\u5de6\u306f\u4ecb\u5165\u7fa4\uff08Intervention\uff09\u3001\u53f3\u306f\u7d71\u5236\u7fa4\uff08Control\uff09 Pre: \u4ecb\u5165\uff08\u5f85\u6a5f\uff09\u524d, Post: \u4ecb\u5165\uff08\u5f85\u6a5f\uff09\u5f8c\u3010 \u8c4a\u5cf6\u3089\uff082024\uff09\u3088\u308a\u3011[2]<\/figcaption><\/figure>\u307e\u305f\u3001\u5c3f\u4e2d\u306e\u7269\u8cea\u3067\u306f\u3001\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u3068\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4ee3\u8b1d\u7269\u304c\u30c0\u30f3\u30b9\u4ecb\u5165\u306b\u3088\u3063\u3066\u5897\u52a0\u3057\u307e\u3057\u305f\uff08\u56f33\uff09\u3002<\/p>\n<figure id=\"attachment_17126\" aria-describedby=\"caption-attachment-17126\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-17126 size-full\" src=\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2024\/10\/Fig3_bio-e1729922368674.jpg\" alt=\"\" width=\"600\" height=\"263\" \/><figcaption id=\"caption-attachment-17126\" class=\"wp-caption-text\">\u56f33\u3000\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\uff08Oxytocin\uff09\u3068\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4ee3\u8b1d\u7269\uff08MHPG\uff09\u306e\u6fc3\u5ea6\u5909\u5316 Intervention: \u4ecb\u5165\u7fa4, Control: \u7d71\u5236\u7fa4, Pre: \u4ecb\u5165\uff08\u5f85\u6a5f\uff09\u524d, Post: \u4ecb\u5165\uff08\u5f85\u6a5f\uff09\u5f8c \u3010\u5c71\u4e0b\u3089\uff082024\uff09\u3088\u308a\u3011[3]<\/figcaption><\/figure>\n<p>\u4eca\u56de\u898b\u51fa\u3055\u308c\u305f\u30a2\u30d1\u30b7\u30fc\u306e\u4f4e\u6e1b\u3001\u304a\u3088\u3073\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u3068\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u5897\u52a0\u306f\u3001\u5f93\u6765\u306b\u306a\u304b\u3063\u305f\u65b0\u305f\u306a\u77e5\u898b\u3067\u3059\u3002\u8cea\u554f\u7d19\u3067\u691c\u51fa\u3055\u308c\u305f\u30a2\u30d1\u30b7\u30fc\u306e\u4f4e\u6e1b\u306f\u3001\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u4f4e\u6e1b\u306e\u89b3\u70b9\u304b\u3089\u91cd\u8981\u3068\u8003\u3048\u307e\u3059\u3002\u306a\u305c\u306a\u3089\u3001\u30a2\u30d1\u30b7\u30fc\u304c\u9ad8\u3044\u3068\u3001\u8a8d\u77e5\u75c7\u306e\u524d\u6bb5\u968e\u3067\u3042\u308b\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u304b\u3089\u8a8d\u77e5\u75c7\u3078\u3068\u79fb\u884c\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304b\u3089\u3067\u3059 [4] 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Asai\u69d8\u3001\u4e95\u4e0a\u798f\u5b50\u69d8\u3001\u5ddd\u5cf6\u5968\u5927\u69d8\u3001\u5b89\u5ca1\u6276\u7d00\u69d8\u3001\u5bae\u7530\u5fe0\u660e\u69d8\u3001\u6d77\u91ce\u771f\u53f8\u69d8\u3001DMG\u68ee\u7cbe\u6a5f\u682a\u5f0f\u4f1a\u793e\u69d8\u3001\u53e4\u5c4b\u967d\u5b50\u69d8\u3001\u6ca2\u7530\u6674\u5f66\u69d8\u3001\u3069\u3058\u3087\u3046\u3059\u304f\u3044\u5973\u5c06\u30fb\u5c0f\u5e61\u7f8e\u9999\u69d8\u3001KAZ\u69d8\u3001\u307f\u3088\u5b50\u69d8\u3001\u30a8\u30c0\u30b7\u30f3\u30a4\u30c1\u69d8\u3001\u539f\u7530\u5eb7\u69d8\u3001\u677e\u539f\u4ec1\u69d8\u3001\u307f\u306a\u3051\u3093\u69d8\u3001\u4f50\u85e4\u9b8e\u7f8e\u69d8\u3001\u5c0f\u5ddd\u96c5\u4eba\u69d8\u3001\u6c5f\u7530\u88d5\u5b50\u69d8\u3001\u53e4\u539f\u751f\u7f8e\u5b50\u69d8\u3001\u524d\u7530\u771e\u91cc\u69d8\u3001\u5409\u5ddd\u8cb4\u4ee3\u69d8\u3001\u30bf\u30b1\u30b6\u30ef\u30e4\u30b9\u30b3\u69d8\u3001Institute for Dementia Care Asia\u69d8\u3001\u5927\u6a4b\u660e\u69d8\u3001\u7c82\u548c\u5f66\u3001EMI MANABE\u69d8\u3001 \u30e2\u30ea\u30e8\u30b7\u30d2\u30ed\u69d8\u3001IMAMURA\u69d8\u3001\u3092\u59cb\u3081\u3068\u3059\u308b105\u540d\u306e\u65b9\u3005\u3067\u3059\u3002\u305d\u306e\u4ed6\u306b\u3001\u533f\u540d\u3067\u306e\u3054\u652f\u63f4\u3082\u9802\u6234\u3044\u305f\u3057\u307e\u3057\u305f\u3002\u3054\u652f\u63f4\u304f\u3060\u3055\u3063\u305f\u3059\u3079\u3066\u306e\u30b5\u30dd\u30fc\u30bf\u30fc\u306e\u7686\u69d8\u306b\u5fc3\u3088\u308a\u611f\u8b1d\u3092\u7533\u3057\u4e0a\u3052\u307e\u3059\u3002<\/p>\n<p><strong>\u5f15\u7528\u6587\u732e<\/strong><\/p>\n<ul>\n<li>[1] Verghese, J., Lipton, R. B., Katz, M. J., Hall, C. B., Derby, C. A., Kuslansky, G., &#8230; &amp; Buschke, H. \uff082003\uff09. Leisure activities and the risk of dementia in the elderly. New England Journal of Medicine, 348\uff0825\uff09, 2508-2516.<\/li>\n<li>[2] \u8c4a\u5cf6\u5f69\u30fb\u9ad8\u677e\u793c\u5948\u30fb\u5ca9\u5d5c\u5531\u5b50\u30fb\u5c71\u4e0b\u96c5\u4fca\u30fb\u6b66\u85e4\u62d3\u4e4b\u30fb\u7a4d\u5c71\u85ab \uff082024\uff09. \u8868\u73fe\u30c0\u30f3\u30b9\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u6291\u3046\u3064\u30fb\u30a2\u30d1\u30b7\u30fc\u306b\u53ca\u307c\u3059\u5f71\u97ff: \u7269\u5fd8\u308c\u306e\u81ea\u899a\u306e\u3042\u308b\u5730\u57df\u9ad8\u9f62\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u4ecb\u5165\u7814\u7a76. \u65e5\u672c\u5fc3\u7406\u5b66\u4f1a\u7b2c88\u56de\u5927\u4f1a\u767a\u8868\u8ad6\u6587\u4e88\u7a3f\u96c6, 2A-030-PD.<\/li>\n<li>[3]\u5c71\u4e0b\u96c5\u4fca\u30fb\u5ca9\u5d5c\u5531\u5b50\u30fb\u8c4a\u5cf6\u5f69\u30fb\u9ad8\u677e\u793c\u5948\u30fb\u7a4d\u5c71\u85ab \uff082024\uff09. \u8868\u73fe\u30c0\u30f3\u30b9\u4ecb\u5165\u304c\u3082\u306e\u5fd8\u308c\u306e\u81ea\u899a\u306e\u3042\u308b\u9ad8\u9f62\u8005\u306e\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u3084\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306b\u53ca\u307c\u3059\u5f71\u97ff. \u65e5\u672c\u5fc3\u7406\u5b66\u4f1a\u7b2c88\u56de\u5927\u4f1a\u767a\u8868\u8ad6\u6587\u4e88\u7a3f\u96c6, 2A-029-PD.<\/li>\n<li>[4] Teng, E., Lu, P. H., &amp; Cummings, J. L. \uff082007\uff09. Neuropsychiatric symptoms are associated with progression from mild cognitive impairment to Alzheimer\u2019s disease. Dementia and geriatric cognitive disorders, 24\uff084\uff09, 253-259.<\/li>\n<li>[5] James, B. D., Wilson, R. S., Barnes, L. L., &amp; Bennett, D. A. \uff082011\uff09. Late-life social activity and cognitive decline in old age. Journal of the International Neuropsychological Society, 17\uff086\uff09, 998-1005.<\/li>\n<li>[6] Holland, N., Robbins, T. W., &amp; Rowe, J. B. \uff082021\uff09. The role of noradrenaline in cognition and cognitive disorders. Brain, 144\uff088\uff09, 2243-2256.<\/li>\n<li>[7] M\u00fcller, P., Rehfeld, K., Schmicker, M., H\u00f6kelmann, A., Dordevic, M., Lessmann, V., &#8230; &amp; M\u00fcller, N. G. \uff082017\uff09. Evolution of neuroplasticity in response to physical activity in old age: the case for dancing. 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