![\"\"](\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2020\/11\/001-a.jpg\")
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E<\/em> \u3068\u3044\u3046\u907a\u4f1d\u5b50\u3092\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3057\u305f\u3068\u304d\u306b\u306f\u3001\u539f\u57fa\u306e\u5f62\u72b6\u306b\u5927\u304d\u306a\u5f71\u97ff\u306f\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u53cd\u9762\u3001\u8868\u9762\u306e\u76ba\u306b\u5f71\u97ff\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n \u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u89d2\u539f\u57fa\u306e\u6298\u308a\u7573\u307f\u306f\u300c\u539f\u57fa\u306e\u5168\u4f53\u306e\u5f62\u72b6\u3092\u6c7a\u3081\u308b\u5927\u307e\u304b\u306a\u6298\u308a\u7573\u307f\u300d\u3068\u300c\u539f\u57fa\u8868\u9762\u306e\u7d30\u304b\u3044\u76ba\u72b6\u306e\u6298\u308a\u7573\u307f\u300d\u306b\u5206\u3051\u3089\u308c\u3001\uff08\u5c11\u306a\u304f\u3068\u3082\u90e8\u5206\u7684\u306b\u306f\uff09\u7570\u306a\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u4f5c\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u3002<\/p>\n \u3055\u3089\u306b\u3001\u8868\u9762\u306e\u76ba\u3078\u306e\u5f71\u97ff\u306f\u3001Notch<\/em> \u3068 Cyclin E<\/em> \u306e\u3069\u3061\u3089\u306e\u907a\u4f1d\u5b50\u3092\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3059\u308b\u304b\u3067\u7570\u306a\u3063\u3066\u304a\u308a\u3001Notch<\/em> \u306e\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3067\u306f\u76ba\u306e\u6df1\u3055\u304c\u6d45\u304f\u306a\u308b\u4e00\u65b9\u3001\u76ba\u306e\u65b9\u5411\u306f\u5909\u308f\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001Cyclin E<\/em> 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[…]<\/p>\n","protected":false},"author":98,"featured_media":14941,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[3],"tags":[53,15,111],"class_list":["post-14931","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-outcome","tag-53","tag-biology","tag-111","has_thumb"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/14931","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/users\/98"}],"replies":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14931"}],"version-history":[{"count":13,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/14931\/revisions"}],"predecessor-version":[{"id":15051,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/posts\/14931\/revisions\/15051"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=\/wp\/v2\/media\/14941"}],"wp:attachment":[{"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14931"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14931"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/academist-cf.com\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14931"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2020\/11\/001-b.jpg\")
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\uff08Matsuda et al. 2017 \u3088\u308a\u6539\u5909\u3057\u3066\u5f15\u7528\uff09<\/figcaption><\/figure>\n\u300c\u6298\u308a\u7573\u307f\u69cb\u9020\u300d\u3092\u4f5c\u308b\u5206\u5b50\u6a5f\u69cb\u3092\u691c\u8a3c<\/h3>\n
![\"\"](\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2020\/11\/002-7.jpg\")
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C\uff09\u5de6\uff1a\u901a\u5e38\u306e\u30aa\u30b9\u306e\u89d2\u539f\u57fa\u306e\u65ad\u9762\u3001\u53f3\uff1adachsous<\/em> \u907a\u4f1d\u5b50\u3092\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3057\u305f\u30aa\u30b9\u306e\u89d2\u539f\u57fa\u306e\u65ad\u9762\u3002dachsous<\/em> \u907a\u4f1d\u5b50\u3092\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3057\u3066\u305f\u500b\u4f53\u3067\u306f\u3001\u539f\u57fa\u5168\u4f53\u306e\u5f62\uff08\u65ad\u9762\u304c\u30ad\u30ce\u30b3\u72b6\uff09\u304c\u5909\u5316\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308b\u3002
\uff08Adachi et al. 2018 \u3088\u308a\u6539\u5909\u3057\u3066\u5f15\u7528\uff09<\/figcaption><\/figure>\n![\"\"](\"https:\/\/academist-cf.com\/journal\/wp-content\/uploads\/2020\/11\/003-6.jpg\")
\uff08Adachi et al. 2020 \u3088\u308a\u6539\u5909\u3057\u3066\u5f15\u7528\uff09<\/figcaption><\/figure>\n
\n\u30fbMatsuda K*, Gotoh H*, Tajika Y, Sushida T, Aonuma H, Niimi T, Akiyama M, Inoue Y, Kondo S. Complex furrows in a 2D epithelial sheet code the 3D structure of a beetle horn. Scientific Reports<\/em>, 7: 13939. 2017 https:\/\/doi.org\/10.1038\/s41598-017-14170-w<\/a>
\n\u30fbAdachi H, Matsuda K, Niimi T, Inoue Y, kondo S, Gotoh H. Anisotropy of cell division and epithelial sheet bending via apical constriction shape the complex folding pattern of beetle horn primordia. Mechanisms of Development<\/em>, 152: 32-37. 2018 https:\/\/doi.org\/10.1016\/j.mod.2018.06.003<\/a>
\n\u30fbAdachi H, Matsuda K, Niimi T, Kondo S, Gotoh H. Genetical control of 2D pattern and depth of the primordial furrow that prefigures 3D shape of the rhinoceros beetle horn. Scientific Reports<\/em>, 10: 18687. 2020. https:\/\/doi.org\/10.1038\/s41598-020-75709-y<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"